DMPK Services: Optimizing Drug Metabolism and Pharmacokinetics
The Drug Metabolism and Pharmacokinetics (DMPK) platform can provide physicochemical properties such as solubility and lipophilicity of compounds, as well as in vivo and in vitro pharmacokinetic data of compounds.Based on this, the chemical structure can be modified to determine whether the biological activity in vitro is sufficient, a reasonable dose range for efficacy and safety evaluation can be further designed, the experimental species can be determined, and the effect of compound crystal form or preparation type on the body can be verified.At present, the platform continues to expand in vitro toxicity experiments, proteomics, PK-PD models, etc., to provide customers with better services.