Protein Kinase Screening

Protein kinase is an important enzyme families in the human gene family. There are 518 species in total, which can be divided into 10 families: TK, STE, TKL, AGC, CMGC, CAMK, RGC, CK1, Atypical and other. Protein kinases are involved in various cell signaling pathways in humans and exert their effects by phosphorylating their respective downstream specific substrate proteins. Abnormal regulation of kinase-mediated signaling pathways is responsible for major human pathological conditions, such as cancer, autoimmune diseases, cardiovascular diseases, neurodegenerative diseases, and metabolic disorders.

 

LeadQuest Biotech’s Advantages in the Field of Kinases

1.Comprehensive Kinase Detection Platform

LeadQuest Biotech has completed a 470+ kinase target detection platform including 22 lipid kinases.

 

2.Diverse Detection Methods

LeadQuest Biotech provide fluorescence-based HTRF, TR-FRET, IMAP FP and chemiluminescence-based ADP-Glo, Kinase-Glo and more; it can also provide IC50 detection under different ATP concentration conditions.